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　　目前逐步聚类作为数据挖掘中的一项重要技术，在医学上得到广泛的应用。

　　At present, as an important technology in data mining, stepwise clustering is widely used in medicine.

　　逐步聚类分析在中医辨证客观化、定量化的研究中，多用于疾病的中医证候分类，为中医临床辨证论治依据提供分型的方法学[1];如张明雪等运用聚类分析等数理统计方法对数据结果进行统计分析，归纳出冠心病合并高血压4 个阶段的证候类型及证候特征[2]。在方剂研究中，动态聚类分析多用于研究方剂中的用药规律、用药方案筛选等相关研究中。周鲁等应用模糊数学中的聚类分析方法，讨论解表类中药之间的相互关系[3]。模糊动态聚类分析也在医学图像处理中得到应用;如田捷等将该方法应用于CT、螺旋CT和MRI等三维医学图像处理与分析，较好识别了薄骨和关节接合处骨骼，重建后三维模型可清晰地再现解剖结构[4]。

　　In the study on objectification and quantification of TCM syndrome differentiation, stepwise clustering analysis is more used in TCM syndrome classification of diseases to provide methodology of classification for TCM clinic treatment based on syndrome differentiation[1];For example, Zhang Mingxue, et al. applied mathematical statistics methods such as clustering analysis to conduct statistical analysis on data results and summed up the types and characteristics of syndromes in four phases of coronary heart disease complicated with hypertension [2]. In the study on prescription, dynamic clustering analysis is more used for the study related to medication rule and screening of medication regimen in the prescriptions, etc. Zhou Lu, et al. applied clustering analysis method in fuzzy mathematics to discuss the mutual relations between the TCMs relieving exterior syndrome [3]. Fuzzy dynamic clustering analysis is also applied in medical image processing; for example, Tian Jie, et al. applied this method to three-dimensional medical image processing and analysis, such as CT, spiral CT and MRI, thus better identifying thin bones and bones at the articulated joints; after rebuilding, the 3D model can clearly reappear the anatomical structure [4].

　　[1]苏晓宇.数据挖掘聚类分析方法在中医临床中的运用[J].实用中西医结合临床，2010 ，10 (6)：90-93

　　[1] Su Xiaoyu. Application of Data Mining Clustering Analysis Method in TCM Clinic[J]. Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine, 2010 ，10 (6)：90-93

　　[2]张明雪，李京，李涵，易丹辉.基于聚类分析的冠心病合并高血压中医证候特征研究[J].中华中医药学刊,2016,34(17):1543-1546

　　[2] Zhang Mingxue, Li Jing, Li Han and Yi Danhui. Study on TCM Syndrome Characteristics of Coronary Heart Disease Complicated with Hypertension based on Clustering Analysis[J]. Chinese Archives of Traditional Chinese Medicine, 2016,34(17):1543-1546

　　[3]周鲁,唐向阳,付超,等.解表类中药的模糊聚类分析[J].华西药学杂志,2004,19(5)：339-341

　　[3] Zhou Lu, Tang Xiangyang, Fu Chao, et at. Fuzzy Clustering Analysis on TCMs Relieving Exterior Syndrome [J]. West China Journal of Pharmaceutical Sciences, 2004,19(5)：339-341

　　[4] 温智, 吴效明, 郭圣文. 基于模糊聚类的医学图像检索方法[J]. 中国医学物理学杂志, 2007,3: 180-183.

　　[4] Wen Zhi, Wu Xiaoming and Guo Shengwen. Retrieval Method of Medical Images based on Fuzzy Clustering [J]. Chinese Journal of Medical Physics, 2007,3: 180-183.